Mononucleosis in Children

Mononucleosis is a viral illness that primarily affects children, teenagers, and young adults. This article will cover what infectious mononucleosis is, its causes, common symptoms, how it is diagnosed and treated, and what parents can do to help prevent it.

If you have concerns about your child’s symptoms or need medical advice, Bootin and Savrick Pediatric Associates is here to help. Schedule an appointment with our experienced pediatricians in Greater Houston today to ensure your child receives the best care possible.

A child sick in bed with a fever caused by mononucleosis in Houston, Texas.

Topic at a Glance

  • Mononucleosis is most commonly caused by the Epstein-Barr virus.
  • It can spread through infected saliva, such as coughing and sneezing.
  • Symptoms include flu-like symptoms and swollen lymph nodes.
  • Treatment focuses on making your child feel comfortable during recovery.

What is Infectious Mononucleosis?

Infectious mononucleosis is a viral illness that affects the immune system by attacking the body’s white blood cells. An Epstein-Barr virus infection most commonly causes it, but other viruses can also lead to the condition.

Mono is contagious and spreads through direct contact with saliva, which is why it is sometimes called the “kissing disease.” However, children can also contract mono through shared utensils, drinking from the same cup, or exposure to infected droplets from coughing or sneezing.

The illness is more commonly seen in adolescents and young adults, especially college students. However, younger children can also develop it.

What Causes Infectious Mononucleosis?

The primary cause of mononucleosis is the Epstein-Barr virus (EBV), a member of the herpesvirus family. Once a person contracts EBV, the virus remains in their body for life, though it typically becomes inactive after the initial infection. By adulthood, most adults have been exposed to the Epstein-Barr virus, even if they never developed noticeable symptoms.

In some cases, other viruses may also cause a mononucleosis-like illness, but EBV is by far the most common cause.

What Are the Symptoms of Infectious Mononucleosis?

Mononucleosis symptoms can vary in severity, but the most common symptoms include:

  • Sore throat
  • Fatigue
  • Fever
  • Swollen lymph nodes in the armpits and neck
  • Headache
  • Swollen tonsils
 

Symptoms of mono can last anywhere from 2 to 4 weeks, but in some cases, fatigue may persist for months. Symptoms can be more severe in those with weakened immune systems.

Complications of mononucleosis

In some severe cases, mononucleosis can cause the following serious complications to occur:

  • Enlarged spleen: This can lead to rupture. Call your child’s doctor if they have sudden pain on the upper left side of their abdomen.
  • Liver problems: Mono can lead to inflammation of the liver (hepatitis) or jaundice

Less common complications of mononucleosis may include the following:

  • Anemia: Low level of red blood cells
  • Thrombocytopenia: A low level of platelets
  • Heart problems: Including inflammation of the heart muscle (myocarditis)
  • Nervous system problems: Possibly including meningitis, Guillain-Barre syndrome, and encephalitis

How is Infectious Mononucleosis Diagnosed?

Diagnoses involve a combination of a physical exam and laboratory tests. During the physical exam, a doctor will check for common symptoms such as swollen lymph glands, an enlarged spleen, or a swollen liver.

A blood test may be conducted to look for signs of infection. This may look for an increased number of white blood cells or the presence of EBV antibodies.

How is Infectious Mononucleosis Treated?

Since mononucleosis is caused by a virus, there is no specific treatment. Antibiotics are not effective as they only treat bacterial infections. Treatment, therefore, focuses on relieving symptoms and making recovery comfortable. Common treatment recommendations include:

  • Rest: You must allow the body time to recover
  • Hydration: Drink plenty of fluids
  • Pain and fever relief: Your child may take age-appropriate over-the-counter medications like acetaminophen or ibuprofen to help with fever and sore throat
  • Gargling with salt water: This can also help soothe a sore throat
 

Most children recover fully within a few weeks, but lingering fatigue can last longer.

Can Infectious Mononucleosis (Mono) Be Prevented?

While there is no vaccine for Epstein-Barr virus, parents can help reduce the risk of mono by encouraging good hygiene practices, such as:

  • Avoid sharing utensils, drinks, or toothbrushes
  • Teaching children to wash their hands frequently
  • Covering their mouths when coughing and sneezing to prevent the spread of viral infections
 

Since EBV remains in the body even after symptoms resolve, individuals who have had mono in the past may still spread the virus intermittently. While complete prevention isn’t always possible, these precautions can help lower the chances of infection.

Helping Your Child Recover from Mono

If your child has been diagnosed with mononucleosis, the best approach is supportive care. Rest, hydration, and symptom management will help them recover comfortably. If symptoms worsen, such as difficulty breathing, severe abdominal pain, or extreme weakness, seek medical attention promptly.

At Bootin and Savrick Pediatric Associates, we have experience treating viral childhood illnesses like mononucleosis and can provide guidance and support for your child’s recovery. If you have concerns about your child’s symptoms or need medical advice, schedule an appointment with our expert pediatricians in Houston, Texas, today. We are committed to providing the best care for your child’s health and well-being.

Medically reviewed by Dr. Monica McGrann

FAQs About Mononucleosis

How long does it take a child to recover from mono?

Most children begin feeling better within 2 to 4 weeks, although fatigue can sometimes last for several weeks or even months after other symptoms have resolved.

It is uncommon to get mono more than once. After infection, the Epstein-Barr virus remains inactive in the body, and the immune system usually prevents the illness from recurring.

Children can generally return to school when they feel well enough and their fever has resolved. However, strenuous exercise and contact sports should be avoided until a doctor confirms it is safe, especially if the spleen is enlarged.

Seek medical care if your child experiences severe abdominal pain, difficulty breathing, trouble swallowing, extreme weakness, dehydration, or symptoms that suddenly worsen.

Yes. The Epstein-Barr virus can remain in the body after symptoms resolve, and some people may continue to shed the virus in their saliva from time to time without feeling sick.